One of the dramas of having a dog is that its life expectancy is short (remember that 7 years does not equal 1 human). But nevertheless, this could be things of the past thanks to rapamycin, which is currently used to prevent rejection in organ transplants, alleviate arterial inflammation in angioplasties, or to treat some types of cancer.
Rapamycin, which is called that because the bacteria from which f is extractedIt was discovered on Easter Island (Rapa Nui), has been shown to prevent cell aging in fruit flies, worms and mice. For example, in July 2009, an article in the magazine Nature It showed that this medicine prolonged the life of some mice by up to 38%. Apparently, rapamycin induces a series of changes at the biochemical level that makes cells believe that they are receiving less nutrients, which makes them enter a lower metabolic state and prolongs their life. Could this property be used in more complex animals such as a dog, which has a higher life expectancy?
In the opinion of the biochemist David Sinclair, from Harvard Medical School, the answer is yes, and therefore they want to study the anti-aging properties of rapamycin in a clinical trial with 32 dogs older than six years. A quarter of the animals will not receive the drug, but a placebo.
It is not yet known if this drug will become a food supplement for our pets. But if the results are as expected, maybe could also begin to be tested on humans.
Other researchers are skeptical. For example, in the case of good results obtained with mice, they argue that these effects on aging are due to the fact that rapamycin inhibits the formation of tumors. Cancer is the leading cause of death in these mouse strains, therefore, it seems to have isolated effects on specific pathologies of aging in mice.